After the Browns kicked a 53-yard field goal, the Broncos offense got to work from their own 9-yard line.
A pair of 9-yard completions to receivers Eric Decker and Demaryius Thomas got the drive started.
On third down from their own 37, quarterback Peyton Manning found tight end Jacob Tamme crossing through the middle of the field. Tamme hit the sideline and gained 33 yards, moving the offense down to the Cleveland 30-yard line.
A play later, wideout Brandon Stokley caught a pass off the hands of Decker, and then running back Knowshon Moreno picked up another first down with an 11-yard burst.
On first-and-goal from the 8, Manning hooked up with Decker for their second touchdown of the game, putting Denver ahead 21-6.
It was Manning’s third touchdown pass of the game – his 72nd career game with three passing touchdowns, which tied Brett Favre for the most in NFL history.
His 34 passing touchdowns on the year are the second-most he has ever thrown for in a single season.
For Decker, who caught his second touchdown of the game, it his third multi-touchdown game in his career. He has six catches for 65 yards.
The touchdown drive took 6:36 and covered 91 yards on 12 plays.