What was once a 24-point lead is now just three after a 55-yard scoring march by the Broncos.
Taking over at its own 45-yard line with easily its best field position of the night, Denver started the drive strong on a 9-yard run by running back Willis McGahee, who added a 2-yard burst for first down yardage on the following play.
The Broncos moved the chains again on third-and-16 when Manning threaded the needle through tight coverage to Jacob Tamme for a 25-yard gain along the sideline.
That play put the ball on the San Diego 25-yard line, where a 9-yard run followed by a 2-yard run, both by McGahee, gave Denver another first down.
On the following play, Manning high-stepped a defender and completed a 7-yard pass to wide receiver Eric Decker. Manning went right back to Decker on a screen pass on the following play, and Decker followed his blockers, then plowed through San Diego defenders on his way into the end zone.
The touchdown makes it three straight games with a receiving touchdown for Decker.
On the evening, Manning is 21-for-26 for 273 yards and two touchdowns for a quarterback rating of 120.0.